Most runs
With 240 runs at 153, Shan Masood is the leading run-getter of Pakistan Super League 2021/22. Masood scored 43 in 31 balls in Multan Sultans' 20-run win over Islamabad United. He is followed by Fakhar Zaman, who has amassed 182 runs at 192. Ahsan Ali is at next, with 154 runs at 143.
| PLAYER | MATCHES | RUNS | AVG | SR |
| Shan Masood | 4 | 240 | 60 | 152.87 |
| Fakhar Zaman | 2 | 182 | 91 | 191.58 |
| Ahsan Ali | 3 | 154 | 77 | 142.59 |
| Mohammad Rizwan | 4 | 133 | 44.33 | 130.39 |
| Will Smeed | 3 | 130 | 43.33 | 127.45 |
Most Wickets
Khushdil Shah took four wickets against Islamabad United to climb to the top of the wickets chart of the tournament. He has taken nine wickets till date. Imran Tahir and David Willey are tied at second place, with seven wickets each, while Naseem Shah has four wickets.
| PLAYER | MATCHES | WKTS | AVG |
| Khushdil Shah | 4 | 9 | 8.11 |
| Imran Tahir | 4 | 7 | 15.29 |
| David Willey | 4 | 7 | 16 |
| Naseem Shah | 3 | 6 | 13.5 |
| Mohammad Nawaz | 3 | 4 | 19 |