Most Runs
With 528 runs in 13 games, Perth Scorchers' Beth Mooney is the leading run-getter of the 2021/22 Women's Big Bash League. She scored 26 against Sydney Sixers. Mooney is followed by Elyse Villani, who scored a century in Melbourne Stars' nine-wicket win over Adelaide Strikers. With 436 runs in 13 matches, Georgia Redmayne is at third place.
| PLAYER | MATCHES | RUNS | AVG | SR |
| Beth Mooney | 13 | 528 | 52.8 | 132 |
| Elyse Villani | 12 | 439 | 43.9 | 122.28 |
| Georgia Redmayne | 13 | 436 | 36.33 | 120.44 |
| Katie Mack | 14 | 426 | 60.86 | 118.01 |
| Mignon du Preez | 14 | 414 | 31.85 | 115 |
Most Wickets
With 21 wickets in 13 matches, Jess Jonassen is the leading wicket-taker of the series. Alana King, Heather Graham, Lilly Mills, Amanda-Jade Wellington and Hannah Darlington are tied at second place with 16 wickets each. King took three wickets Sydney Sixers.
| PLAYER | MATCHES | WKTS | AVG |
| Jess Jonassen | 13 | 21 | 14.05 |
| Alana King | 13 | 16 | 16.75 |
| Heather Graham | 13 | 16 | 16.88 |
| Hannah Darlington | 13 | 16 | 20.75 |
| Lilly Mills | 13 | 16 | 12.81 |
| Amanda Wellington | 14 | 16 | 19.94 |